Wayne State University

Functional Fluidics

Conditions associated with vascular thrombosis and adhesion can be difficult to diagnose, treat, and monitor. Thrombosis formation is a complex process that responds to many variables in both the composition of the blood, as well as the pulsatile flow conditions in the vessel.  Functional Fluidics is developing novel devices and protocols to address the need for measuring thrombosis and adhesion formation in whole blood under pulsatile flow.


Functional Fluidics’ assay can assess the behavior of blood while it is flowing, and mimics in vivo behavior while currently available tests use in vitro methods.  The system uses micro-fluidics to analyze whole blood adhesion and thrombosis and is a much better predictor of blood behavior physiologically.

patrick hines

Dr. Patrick Hines, Founder of Functional Fluidics, was interested in using The SearchLite’s knowledge gathering services to understand potential field applications as well as the Industry Ecosystem for this technology.  The inventor team  wanted to look beyond indications including:

  • Atrial fibrillation (AF)
  • Deep vein thrombosis (DVT)
  • Sickle cell anemia (SCA).


Several Market Application Profiles were submitted and shaped by Innovators-in-Residence (IIRs) and Mentors-in-Residence (MIRs) from The SearchLite Community. Participants commented and voted on alternative Customer Segments as to their Product-Market Fit with the Functional Fluidics Technology Benefits and Value Proposition.   One of the MIRs (Scott Olson) led the community to discovery the clinical role of the Perfusionists within the technology adoption dynamics associated with the Functional Fluidics solution during surgery.


visha krishnan

One of the IIRs (Visha Krishnan) “Given the ability of the functional fluidic device to test beyond thrombrosis, it might be a better product for hematological analyses.”  “Telemedicine” was voted as the most promising Customer Segment for further investigation.  The Outputs included:

  • Primary Research with synthesis of technology adoption insights from key industry experts
  • Secondary Research with industry articles and presentations
  • Actionable Next steps and Recommendations

The SearchLite identified several customer segments that we had not considered.  In a couple of cases, they also drilled down to uncover insights relative to industry practices that are relevant to new product commercialization.

—— Dr. Patrick Hines

Founder Functional Fluidics

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